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Approaches of Systems Biology of Metabolically Engineered Crops Enriched in β-Carotene Content

Published on May 23, 20132964 Views

Carotenoids are secondary metabolites involved, in animals, in the prevention of several animal diseases including cancers and cardio-vascular pathologies. In plants, they play essential functions as

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Approaches of Systems Biology of Metabolically Engineered Crops Enriched in β-Carotene Content00:00
ENEA “CASACCIA” research centre00:23
Introduction - 102:26
Introduction - 203:13
Nutrition in developing countries and non developing03:14
Copenhagen Consensus 2008 list of priorities - 105:02
Copenhagen Consensus 2008 list of priorities - 205:47
Copenhagen Consensus 2008 list of priorities - 306:38
Copenhagen Consensus 2008 list of priorities - 407:27
Why Metabolic Engineering (ME) for Biofortification? - 107:56
Why Metabolic Engineering (ME) for Biofortification? - 208:07
Why Metabolic Engineering (ME) for Biofortification? - 308:26
Why Metabolic Engineering (ME) for Biofortification? - 408:40
Why Metabolic Engineering (ME) for Biofortification? - 508:48
…before starting a metabolic engineering program…09:29
…and after getting a bio-GM-fortified food…10:35
How do endogenous pathway work? - 110:35
How do endogenous pathway work? - 212:11
How do endogenous pathway work? - 312:45
Bio-fortification strategies, via metabolic engineering, for crop improvement 12:46
Introduction - 315:07
Carotenoid distribution and their functions in plants - 115:10
Carotenoid distribution and their functions in plants - 215:36
Carotenoid distribution and their functions in plants - 316:23
Carotenoids in nutrition - 117:35
Carotenoids in nutrition - 217:37
Biosynthesis of carotenoids and their derivatives18:15
Metabolic engineering of plant carotenoids19:48
Golden Rice (I and II) - 120:28
Golden Rice (I and II) - 221:48
Golden Rice (I and II) - 221:50
Metabolic engineering of carotenoids in potato: block strategy - 122:25
Metabolic engineering of carotenoids in potato: block strategy - 223:22
Metabolic engineering of carotenoids in potato: block strategy - 323:55
Metabolic engineering of carotenoids in potato: Crt push strategy24:16
Crt gene overespression effects in adult leaves25:10
Crt gene overespression effects in mature tubers27:27
Golden Potatoes to fight vitamin A deficiency?30:18
The “Sink” strategy: the “Or” mutation30:53
Metabolic engineering of carotenoids in tomato: push strategy - 132:10
Metabolic engineering of carotenoids in tomato: push strategy - 232:47
Metabolic engineering of carotenoids in tomato: push strategy - 333:09
Metabolic engineering of carotenoids in tomato: push strategy - 433:16
Effects on endogenous Transcrips/metabolites in tomato flowers 33:51
Effects on endogenous Transcrips/metabolites in tomato fruits - 134:08
Effects on endogenous Transcrips/metabolites in tomato fruits - 234:28
Alterated emission profiles of volatile metabolites in tomato transgenics - 135:48
Alterated emission profiles of volatile metabolites in tomato transgenics - 235:50
Alterated emission profiles of volatile metabolites in tomato transgenics - 335:51
Introduction - 435:53
How to better investigate metabolic engineered plant products? - 136:04
How to better investigate metabolic engineered plant products? - 236:39
Transcriptomic, metabolomic and phenomic profiling36:56
Metabolomic analyses at ENEA - 137:58
Metabolomic analyses at ENEA - 241:41
Metabolomic analyses at ENEA - 342:14
Metabolomic analyses at ENEA - 442:40
Metabolomic analyses at ENEA - 543:10
Transcript-Metabolite Correlation Matrix in Crt tubers - 143:51
Transcript-Metabolite Correlation Matrix in Crt tubers - 245:28
Transcript-Metabolite Correlation Matrix in Crt tubers - 345:54
Transcript-Metabolite Correlation Matrix in Crt tubers - 445:57
Correlation Networks (“local” biology) - 146:43
Correlation Networks (“local” biology) - 246:44
Correlation Networks (“local” biology) - 347:25
What’s Next? - 147:37
What’s Next? - 247:57
What’s Next? - 348:08
beta-carotene enriched tubers by classic breeding program48:18
Pleiotropic effects in Crt potatoes - 149:20
Pleiotropic effects in Crt potatoes - 249:21
Metabolome alterations in “Golden” potatoes50:28
Regulatory network linking - 151:02
Regulatory network linking - 251:03
Regulatory network linking - 351:15
Regulatory network linking - 451:37
Regulatory network linking - 551:44
Regulatory network linking - 651:52
Pleiotropic effects on fruit ripening of tomato transgenics52:16
Correlation Networks (“global” biology) - 153:00
Correlation Networks (“global” biology) - 253:01
Significant modules in a correlation network… - 153:45
Significant modules in a correlation network… - 253:45
Significant modules in a correlation network… - 353:48
400 genes+metabolites+phenotypic data (LCY-b tomato ripe fruits) - 154:13
400 genes+metabolites+phenotypic data (LCY-b tomato ripe fruits) - 254:13
400 genes+metabolites+phenotypic data (LCY-b tomato ripe fruits) - 354:15
Future perspectives in carotenoid metabolic engineering field… - 154:59
Future perspectives in carotenoid metabolic engineering field… - 255:04
Future perspectives in carotenoid metabolic engineering field… - 355:42
Metabolic flux analysis - 156:22
Metabolic flux analysis - 256:23
Metabolic flux analysis - 356:24
Conclusions - 156:58
Conclusions - 257:16
Acknowledgements - 157:18
Acknowledgements - 257:42
Acknowledgements - 357:54
Thank you for your attention58:00